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Tetsuo Kiso Selected Research

N- (1- methyl- 2- oxo- 1,2,3,4- tetrahydro- 7- quinolyl)- 2- ((2- methylpyrrolidin- 1- yl)methyl)biphenyl- 4- carboxamide

3/2011Amelioration of neuropathic pain by novel transient receptor potential vanilloid 1 antagonist AS1928370 in rats without hyperthermic effect.
1/2011Intrathecal administration of AS1928370, a transient receptor potential vanilloid 1 antagonist, attenuates mechanical allodynia in a mouse model of neuropathic pain.

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Tetsuo Kiso Research Topics

Disease

10Hyperalgesia
08/2020 - 08/2003
8Neuralgia (Stump Neuralgia)
10/2018 - 01/2011
7Pain (Aches)
01/2021 - 08/2003
4Myalgia
01/2021 - 05/2018
4Chronic Pain
08/2020 - 09/2007
3Osteoarthritis
01/2021 - 11/2017
2Acute Pain
08/2020 - 01/2011
2Fibromyalgia (Fibrositis)
10/2018 - 05/2018
2Constipation
04/2003 - 08/2002
1Abdominal Pain (Pain, Abdominal)
01/2021
1Arthritis (Polyarthritis)
10/2018
1Diabetic Neuropathies (Diabetic Neuropathy)
11/2017
1Type 2 Diabetes Mellitus (MODY)
03/2011
1Insulin Resistance
03/2011

Drug/Important Bio-Agent (IBA)

8Analgesics (Analgesic Drugs)IBA
01/2021 - 08/2003
4Reserpine (Serpasil)FDA Link
01/2021 - 05/2018
4N-Type Calcium Channels (N-Type Calcium Channel)IBA
08/2015 - 05/2010
3Streptozocin (Streptozotocin)FDA Link
10/2018 - 09/2007
3Duloxetine Hydrochloride (Cymbalta)FDA Link
05/2018 - 05/2010
3Pregabalin (Lyrica)FDA Link
05/2018 - 05/2010
3Capsaicin (Zostrix)FDA Link
11/2017 - 01/2011
3Freund's AdjuvantIBA
03/2011 - 08/2003
3LigandsIBA
03/2011 - 05/2010
2ProstaglandinsIBA
08/2020 - 11/2017
2AcidsIBA
08/2020 - 11/2017
2ASP8477IBA
08/2020 - 11/2017
2BicucullineIBA
08/2020 - 05/2010
2alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
08/2020 - 11/2017
2N-Methylaspartate (NMDA)IBA
08/2020 - 05/2010
2ziconotide (Prialt)FDA Link
12/2014 - 05/2010
2TRPV1 receptorIBA
03/2011 - 01/2011
2Protons (Proton)IBA
03/2011 - 01/2011
2Dihydrotachysterol (AT 10)IBA
03/2011 - 01/2011
2N- (1- methyl- 2- oxo- 1,2,3,4- tetrahydro- 7- quinolyl)- 2- ((2- methylpyrrolidin- 1- yl)methyl)biphenyl- 4- carboxamideIBA
03/2011 - 01/2011
22- (1H- imidazol- 4- ylmethyl)- 8H- indeno(1,2- d)thiazoleIBA
04/2003 - 08/2002
1Indicators and Reagents (Reagents)IBA
01/2021
1anandamide (arachidonylethanolamide)IBA
08/2020
1fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
08/2020
1Cannabinoid Receptor AgonistsIBA
08/2020
1EnzymesIBA
10/2018
1ASP3662IBA
10/2018
1GlucocorticoidsIBA
10/2018
1Hormones (Hormone)IBA
10/2018
1Oxidoreductases (Dehydrogenase)IBA
10/2018
1Neurotransmitter Agents (Neurotransmitter)IBA
05/2018
1CannabinoidsIBA
11/2017
1Iodoacetic AcidIBA
11/2017
1AS2717638IBA
11/2017
1geranylgeranyl pyrophosphate (geranylgeranyl diphosphate)IBA
11/2017
1SecretagoguesIBA
03/2011
1Insulin (Novolin)FDA Link
03/2011
1Glucose (Dextrose)FDA LinkGeneric
03/2011
1Mexiletine (Mexitil)FDA LinkGeneric
05/2010
1GABA-A Receptors (GABA(A) Receptor)IBA
05/2010
1gamma-Aminobutyric Acid (GABA)IBA
05/2010
1Calcium Channels (Calcium Channel)IBA
05/2010
1Dinoprostone (PGE2)FDA Link
05/2010
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
05/2010
1Glutamic Acid (Glutamate)FDA Link
05/2010
1Sodium Channel BlockersIBA
05/2010
1Serotonin and Noradrenaline Reuptake InhibitorsIBA
05/2010
1(R)- N- cycloheptyl- 6- ((((tetrahydro- 2- furyl)methyl)amino)methyl)thieno(2,3- d)pyrimidin- 4- ylamineIBA
09/2007
1Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
09/2007
1Indomethacin (Indometacin)FDA LinkGeneric
08/2003
1Tramadol (K315)FDA LinkGeneric
08/2003
1Amitriptyline (Elavil)FDA LinkGeneric
08/2003
1Morphine (MS Contin)FDA LinkGeneric
08/2003
1Diclofenac (SR 38)FDA LinkGeneric
08/2003
1ThiazolesIBA
04/2003

Therapy/Procedure

8Ligation
08/2020 - 01/2011
5Oral Administration
08/2020 - 08/2015
1Vagotomy
01/2021
1Therapeutics
11/2017
1Spinal Injections
11/2017